Mr Engle has executive leadership experience with public and private biotechnology companies developing breakthrough products in metabolic, autoimmune, oncologic and infectious disease areas. Most recently, Steve was the CEO of Gradalis, a biotechnology company focused on the development of personalized cellular immunotherapies to treat cancer, and which is preparing a clinical study for product registration in patients with ovarian cancer. Prior to that, he was the CEO of CohBar, a clinical-stage biotechnology company developing mitochondria-based therapeutics to treat chronic diseases and extend healthy lifespan. Previously, he served as Chairman and CEO of antibody therapeutics company XOMA, which developed antibody drug candidates for many of the major pharmaceutical companies, and of B-cell tolerance therapeutics company, La Jolla Pharmaceutical Company, which discovered the biology of B cell tolerance and developed the first B cell toleragen for lupus patients. Earlier, he served as Vice President of Marketing for Cygnus, a drug delivery systems company, where he helped to gain FDA approval of and to launch Nicotrol for smoking cessation. He is member of the board of New Zealand based Author-it Software Corporation, a developer of authoring information solutions for pharmaceutical and biotechnology companies. He is a former director of industry associations, BIO, BayBio and BIOCOM, and was a member of the board of the Lupus Foundation of America. Other current directorships include Author-It Software Company. Former directorships (last 3 years): Gradalis, CohBar (NASDAQ:CWBR). He is Member of Risk Committee.
